Textbook

2nd edition, 2011

14 Sections – 195 Chapters –
370 Contributing authors from 34 countries

Following the success of the 1st edition of the Textbook of Gynaecological Oncology published in 2009, the 2nd edition has taken this highly acclaimed publication a step further. Original chapters were revised by all authors, adapted according to feedback on the first edition and the new increased content reflects the evolving needs of the community of gynae-oncologists in training.

This unique, comprehensive and practical book is written by the best specialists in the field and provides a concise update of current clinical gynaecologic oncology including surgery, radiotherapy, chemotherapy and imaging specialties as well as reviews of multinational trials. The textbook is up to date, including the most recent literature and brand new statistics.

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SECTION I: PREINVASIVE DISEASES
- 1. Vulvar Dermatoses: Non-Neoplastic Epithelial Disorders of the Vulva
  Libby Edwards, MD
- 2. Preinvasive Diseases of Vulva and Vagina
  Allan B. MacLean, MD, MRCOG.
- 3. Cervicovaginal Cytology: Normal and Abnormal Cells and Adequacy of Specimens
  Christine Bergeron, MD, PhD
- 4. Cervical Pre-Invasive Disease
  Vesna Kesic‘, MD, PhD
- 5. The Basic Principles of Colposcopy
  David Luesley, MA, MD, FRCOG
- 6. Colposcopic Findings for Glandular Lesions
  Damian Dexeus,MD, Santiago Dexeus, MD Montserrat Cararach, MD
- 7. How to Manage Pre-Invasive Cervical Diseases?An Overview
  Ali Ayhan, MD, Mufit C. Yenen, MD, Murat Dede, MD, Polat Dursun, MD, Murat Gultekin, MD
- 8. Management of CIN in Pregnancy
  Vena Kesic‘, MD, PhD
- 9. Guidelines for Pre-Invasive Cervical Lesions: USA vs Europe
  Yin Ling Woo, MD, PhD, MRCOG Mahmood I. Shafi, MBBCh, MD, FRCOG.
- 10. Treatment Modalities for Cervical Pre-Invasive Lesions
  Gokhan Tulunay, MD, Nejat Ozgul, MD
- 11. Cold Knife Conization: Technique and Results
  Kersti Kukk, MD, Liidia Gristsenko, MD
- 12. Management of Margin Positive Cases After Loop Electrosurgical Excision Procedure
  Firat Ortac, MD, Mete Gungor, MD, Salih Taskin, MD
- 13. Benign Endometrial Hyperplasia and Endometrial Intraepithelial Neoplasia (EIN)
  George L. Mutter, MD
- 14. Treatment of Endometrial Hyperplasia
  George Vorgias, MD, PhD, Stelios Fotiou, MD, PhD
SECTION II: HPV AND CERVICAL CARCINOGENESIS
- 15. HPV Infection and Cervical Carcinogenesis: Epidemiology and Prevention
  Alexandra de Pokomandy, MDCM, MSc, Eduardo L. Franco, PhD
- 16. HPV Related Non-Cervical Cancers
  Tengiz Charkviani, MD, Nino Kekelidze, MD Irina Dvalishvili, MD
- 17. Clearance of HPV Genotype
  Sian Taylor, BSc, MRCOG, John A. Green, MD, FRCP
- 18. Prevalence of Human Papillomavirus Infection and Burden of Cervical Cancer in Europe in 2008
  Marc Arbyn, MD, MSc, DrTMH, Laia Bruni, MD, MPH Silvia de Sanjosé, MD, PhD, Peng Guan, PhD Jacques Ferlay, ME, Freddie Bray, PhD
- 19. The Spectrum and Clinical Sequelae of Human Papillomavirus Infection
  Krishnansu S. Tewari, MD, FACOG, FACS Bradley, J. Monk, MD, FACOG, FACS
- 20. Condylomas & Evidence-Based Review of Medical and Surgical Treatments of Genital Warts
  Eleonora P.Preti, MD, Mario Sideri, MD
- 21. HPV-Based Cervical Cancer Screening
  Chris J.L.M. Meijer, MD, PhD, Dorien C. Rijkaart, PhD Johannes Berkhof, PhD, Peter J.F. Snijders, PhD, Karl-Ulrich Petry, MD, PhD, Marc Arbyn, MD, MSc, DrTMH - Click here to view this chapter for free
- 22. New Technologies for Cervical Cancer Screening
  Maribel Almonte, PhD, Jack Cuzick, PhD
- 23. Cervical Cancer Screening in The Era of HPV Vaccination
  Goran Dimitrov, MD, MSc, Ana Micevska, MD
- 24. Bivalent HPV Vaccine Approved for Cervical Cancer Prevention in Females
  Diane M. Harper, MD, MPH, MS, Stephen L. Vierthaler, MD
- 25. Quadrivalent HPV Vaccine Approved for Males and Females for HPV Associated Diseases
  Diane M. Harper, MD, MPH, MS, Stephen L. Vierthaler, MD
- 26. Cost-Effectiveness of HPV Vaccination
  Mireia Diaz, MSc, F. Xavier Bosch, MD
- 27. Immune Therapies for HPV Disease
  Michelle Khan, MD, Mihaela Paradis, BA, CCRP Cornelia L. Trimble, MD
SECTION III: BASICS OF GYNAECOLOGICAL CANCERS
- 28. Molecular Basis of Gynecologic Cancers
  Zvi Vaknin, MD, Walter H. Gotlieb, MD, PhD
- 29. Genetics in Gynecologic Oncology
  Rachel Michaelson-Cohen, MD, Uziel Beller, MD
- 30. Hereditary Breast Cancer Risk and Genetic Counseling
  Banu Arun, MD
- 31. Recent Advancements in the Field of Ovarian Cancer Stem Cells
  Moorthy P. Ponnusamy, PhD, Parthasarathy Seshacharyulu, PhD, Surinder K. Batra, PhD
- 32. Gynecologic Oncology.
  Karim S. ElSahwi, MD, Alessandro D. Santin, MD
- 33. Nutrition and Gynaecologic Cancers
  Murat Gultekin, MD, Esra Gultekin, Dietician
- 34. Fundamentals of Cancer Registration: What Can It Offer at a Regional Level?
  Micha Barchana, MD, MPH, Michael Silbermann, DMD, PhD
- 35. Global Burden of Gynaecological Cancer
  Rengaswamy Sankaranarayanan, MD, Jacques Ferlay, ME
- 36. Prevention of Gynecologic Cancers
  Satoru Sagae, MD, Nobuyuki Susumu, MD Aikou Okamoto, MD, Mitsuru Mori, MD
- 37. Prognostic Factors for Gynecologic Cancers
  Okechukwu A. Ibeanu, MD, MPH, Robert E. Bristow, MD, MBA
- 38. Screening for Gynaecological Cancers
  Ranjit Manchanda, MRCOG, Usha Menon, MD, FRCOG
- 39. Circulating Tumor Markers in Gynecological Oncology
  Kunter Yuce, MD, Husnu Celik, MD
- 40. Proteomics in Gynaecologic Oncology
  Toon Van Gorp, MD, Isabelle Cadron, MD Ignace Vergote, MD, PhD
- 41. Imaging in Gynaecologic Oncology
  Perry W. Grigsby, MD
- 42. Role of Ultrasound in Evaluation of Cervical and Endometrial Cancers
  Adrius Gaurilcikas, MD, Daiva Vaitkiene, MD, Antonia Testa, MD
- 43. Menopausal Hormone Therapy and Risk of Cancer
  Peter Bösze, MD
- 44. Statistics for the Beginners in Gynaecologic Oncology
  Alexia Iasonos, PhD
- 45. Unanswered Questions in Gynecologic Oncology
  Lucas Minig, MD, Edward L. Trimble, MD, MPH
SECTION IV: PATHOLOGY
- 46. Pathology for Gynaecologic Oncologists
  Suha Deen, FRCPath
- 47. Diagnostic Immunohistochemistry in Gynecologic Pathology: A Brief Review of Common Clinical Applications
  Joseph T. Rabban MD, MPH, Olge B. Ioffe, MD
- 48. Controversial Diagnoses in Gynaecological Oncology and Clinical Implications
  Suha Deen, FRCPath
- 49. Krukenberg Tumors and Pseudomyxoma Peritonei and Differentiation of Ovarian Tumor
  Soon-Beom Kang, MD,PhD ,Taek-Sang Lee, MD
- 50. Role of Frozen Section in Gynecological Oncology
  Emanuela D’Angelo, MD, Anna Mozos, MD Alberto Gallardo, MD, Jaime Prat, MD, FRCPath
- 51. Pathology of Endometrial Carcinoma
  Raji Ganesan, MD
- 52. Uterine Sarcomas
  Esther Oliva, MD
- 53. Pathology of Vulval and Vaginal Cancers
  Godfrey E. Wilson, MD
- 54. The Pathology of Cervical Cancer
  Michael Scott, MD, FRCPath
- 55. Pathology of Malignant and Borderline Ovarian Tumours
  Naveena Singh, MD, FRCPath
- 56. Pathology of Gestational Trophoblastic Disease
  Elizabeth Benjamin, MBBS, FRCPath
- 57. How to Report a Pathology Specimen in Gynaecologic Oncology?
  Ayse Ayhan, MD, PhD
SECTION V: INVASIVE DISEASES
- 58. Early Stage Cervical Cancers
  Macit Arvas, MD
- 59. Advanced Cervical Cancer
  Simone Marnitz, MD, Christhardt Köhler, MD
- 60. Endometrial Cancer
  Stefano Uccella, MD, Fabio Ghezzi, MD Jamie N. Bakkum-Gamez, MD, Andrea Mariani, MD
- 61. Treatment of Advanced and Recurrent Endometrial Cancers
  Ingrid Vandenput, MD, Lieve Coenegrachts, MD Frederic Amant, MD, PhD
- 62. Uterine Serous Carcinomas
  Peter E. Schwartz, MD, Alessandro D. Santin, MD Pei Hui, MD, PhD
- 63. Uterine Clear Cell Carcinomas
  Christina Fotopoulou, MD, PhD Werner Lichtenegger, MD, PhD
- 64. The Management of Uterine Sarcomas
  Nicholas Reed, MD
- 65. Adnexal Mass: Evaluation and Treatment
  Jennifer Cho, MD, Farr Nezhat, MD, FACOG, FACS
- 66. Role of Ultrasound in the Evaluation of Adnexal Masses
  Juan L. Alcázar, MD, PhD, Matías Jurado, MD, PhD
- 67. Borderline Tumors of the Ovary
  Janina Markowska, MD, PhD, Jacek P. Grabowski, MD, PhD
- 68. The Origin and Pathogenesis of Epithelial
  Ovarian Cancer Natalie Banet, MD, Ie-Ming Shih, MD, Robert J. Kurman, MD
- 69. Early Stage Epithelial Ovarian Cancer
  Lucas Minig, MD, Nicoletta Colombo, MD
- 70. Advanced Stage Epithelial Ovarian Cancers
  Ali Ayhan, MD, Polat Dursun, MD, Murat Gultekin, MD
- 71. Metastatic Ovarian Cancers
  Sung-Jong Lee, MD, PhD, Jeong-Hoon Bae, MD, PhD Ah-Won Lee, MD, PhD, Jong-Sup Park, MD, PhD
- 72. Ovarian Germ Cell Tumours
  Danny Ulahannan, MD, Gordon J.S. Rustin, MD, Msc, FRCP
- 73. Sex Cord-Stromal Tumors of the Ovary
  Michele Peiretti, MD, PhD, Nicoletta Colombo, MD
- 74. Primary Peritoneal Carcinoma
  Giovanni Di Vagno, MD, Stefano Greggi, MD, PhD Cono Scaffa, MD, PhD
- 75. Vulval Cancer
  Alberto D.B. Lopes, FRCOG, Nagindra Das, MRCOG
- 76. Vaginal Cancers
  Neville F. Hacker, MD
- 77. Gestational Trophoblastic Diseases
  S. Sinan Ozalp, MD, Tufan Oge, MD
- 78. Fallopian Tube Neoplasms
  Helena Robova, MD, PhD
- 79. Neuro-Endocrine Tumours of Gynaecological Tract
  Nicholas Reed, MD
- 80. Pregnancy and Cancer
  Vesna Kesic‘, MD, PhD, Lukas Rob, MD, PhD Michael J. Halaska, MD, PhD
- 81. Cervical Cancer During Pregnancy
  Lukas Rob, MD, PhD, Michael J. Halaska, MD, PhD Helena Robova, MD, PhD
- 82. Ovarian Malignancies in Pregnancy
  Alain G. Zeimet, MD, PhD, Christian Marth, MD, PhD
- 83. Pregnancy Associated Breast Cancer
  Sileny N. Han, MD, Kristel Van Calsteren, MD, PhD Frederic Amant, MD, PhD
SECTION VI: SURGERY IN GYNAECOLOGIC ONCOLOGY
- 84. Surgical Anatomy in Pelvic Gynecologic Oncology
  Hugo R. Gasper, MD
- 85. Fertility Preservation for Gynecologic Cancer Patients
  Alexandros Rodolakis, MD, PhD
- 86. Radical Trachelectomy
  Achim Schneider, MD, Evrim Erdemoglu, MD
- 87. Fertility-Sparing Radical Abdominal Trachelectomy for Cervical Carcinoma
  Nadeem R. Abu-Rustum, MD - Click here to view this chapter for free
- 88. Chemo-Conization for Early Staged Cervical Cancer
  Anna Festi, MD, Fabio Landoni, MD
- 89. Role of Lymphadenectomy in Gynaecologic
  Pierluigi Benedetti Panici, MD, Violante Di Donato, MD Plotti Francesco, MD, Stefano Basile, MD Flaminia Gallegati, MD, Filippo Bellati, MD
- 90. Lymphatic Mapping and Sentinel Node Biopsy in Gynecologic Cancers
  Michael Frumovitz, MD, MPH
- 91. Surgical Techniques for Vulvar Cancer
  Neville F. Hacker, MD, Penny Blomfield, MD
- 92. Minimally Invasive Surgery in Gynecologic Oncology
  Fabio Ghezzi, MD, Antonella Cromi, MD, PhD Stefano Uccella, MD, Andrea Mariani, MD
- 93. Management of Incompletely Operated Gynecological Malignancies
  Tayfun Gungor, MD, Mine K. Pektas, MD, Mustafa Besli, MD Mustafa Ozat, MD, Ilkkan Dunder, MD
- 94. Principles of Laparoscopic Surgery
  Lilian T. Gien, MD, MSc, FRCSC, Allan Covens, MD, FRCSC
- 95. Laparoscopic Surgeries in Gynaecological Oncology
  Eric Leblanc, MD, Denis Querleu, MD Fabrice Narducci, MD, Vanessa Samouelian, MD Loic Boulanger, MD, Gwenael Ferron, MD
- 96. Single-Port Surgery for Gynecologic Oncology
  Lori E. Weinberg, MD, Amanda N. Fader, MD Pedro F. Escobar, MD
- 97. Laparoscopic Hysterectomy: A Standardized Technique
  Michel Canis, MD, PhD, Revaz Botchorishvili, MD Benoît Rabischong, MD, Kris Jardon, MD Nicolas Bourdel, MD, Gerard Mage, MD
- 98. Classification System of Radical Hysterectomy
  David Cibula, MD, PhD
- 99. Technique for Abdominal Radical Hysterectomy
  Alejandra Martinez, MD, Gwenal Ferron, MD Denis Querleu, MD, Pedro T. Ramirez, MD
- 100. Introduction of Robotic Surgery: Pitfalls and Future
  Gokhan S. Kilic, MD, Mostafa Borahay, MD John Y. Phelps, MD, JD
- 101. Robotic Surgery in Gynecologic Oncology
  Alberto Mendivil, MD, John F. Boggess, MD
- 102. Robotic Radical Hysterectomy: Surgical Technique
  Javier F. Magrina, MD
- 103. Technique on Laparoscopic Radical Hysterectomy and Comparison of Three Techniques: Laparotomy, Laparoscopy and Robotics
  Amy Tang, MBBS, FRANZCOG Andreas Obermair, MD, MBBS, FRANZCOG, CGO
- 104. New Surgical Approaches for the Management of Cervical Carcinoma
  Polat Dursun, MD, Murat Gultekin, MD, Ali Ayhan, MD Bulent Ozcelik, MD
- 105. Compartment Resection in Gynecologic Oncology: TMMR and LEER
  Michael Höckel, MD, Rainer Kimmig, MD
- 106. Nerve-Sparing Surgery in Cervical Carcinoma
  Shingo Fujii, MD, PhD
- 107. Laparoscopic Extraperitoneal Aortic Dissection
  Denis Querleu, MD, Eric Leblanc, MD
- 108. The Laterally Extended Parametrectomy (LEP)
  László Pálfalvi, MD, PhD, László Ungár, MD, PhD, MHCOG
- 109. Pelvic Exenteration
  László Pálfalvi, MD, PhD, László Ungár, MD, PhD, MHCOG
- 110. Technique of Laparoscopic Exenteration
  Christophe Pomel, MD, Alejandra Martinez, MD Gwenael Ferron, MD
- 111. Flap Reconstruction Following Gynecologic Tumor Resection
  Sara Isani, MD, Gary L. Goldberg, MD
- 112. Colorectal Surgery in Gynecologic Oncology
  Luis M. Chiva, MD, PhD, Matias Jurado, MD, PhD
- 113. The Role of Neobladder Reconstruction in Gynaecologic Oncology
  Sonsoles Alonso, MD, Matías Jurado, MD, PhD Luis M. Chiva, MD, PhD
- 114. Types of Urinary Diversions
  Jeremie de Troyer, MD, Marie Bannier, MD Gilles Houvenaeghel, MD
- 115. Primary Cytoreduction: Factors Impacting Operability and The Extent of Surgery
  Giovanni D. Aletti, MD, William A. Cliby, MD
- 116. Debulking Surgery in Advanced Ovarian Cancer
  Jalid Sehouli, MD, PhD, Christina Fotopoulou, MD, PhD Jacobus Pfisterer, MD, PhD, Philipp Harter, MD Andreas du Bois, MD, PhD
- 117. Upper Abdominal Cytoreduction for Advanced Ovarian Cancers
  Scott M. Eisenkop, MD, Christina L. Kushnir, MD Nick M. Spirtos, MD
- 118. Technique of Liver Resection in Cytoreductive Surgery for Advanced Ovarian Cancer
  Okechukwu A. Ibeanu, MD, MPH, Robert E. Bristow, MD, MBA
- 119. Techniques of Diaphragmatic Surgery
  Jens Einenkel, MD
- 120. Splenectomy and Distal Pancreatectomy
  Faruk M. Kose, MD, Taner A. Turan, MD, Ali Haberal, MD
- 121. Video-Assisted Thoracic Surgery
  Ram Eitan, MD, Dennis S. Chi, MD
- 122. Secondary Cytoreduction
  Philipp Harter, MD, Florian Heitz, MD Christina Fotopoulou, MD, PhD, Jalid Sehouli, MD, PhD
- 123. Tertiary Cytoreduction
  Mario M. Leitao, Jr., MD
- 124. Hysteroscopy in Endometrial Cancer
  Milos Mlyncek, MD, PhD, Erik Lajtman, MD
- 125. Classification of Complications in Gynecological Malignancies Treatments
  Paolo Zola, MD, PhD, Elisa Piovano, MD Stefania Perotto, MD, Paola Modaffari, MD, Elisa Tripodi, MD Valentina Zanfagnin, MD, Luca Fuso, MD Annamaria Ferrero, MD, PhD
SECTION VII: MEDICAL ONCOLOGY
- 126. Basic Principles of Chemotherapy and Drugs Used
  Rosalie Fisher, MBChB, FRACP, Martin E. Gore, PhD, FRCP
- 127. The Role of Chemotherapy in Gynecologic Malignancies
  Leslie Boyd, MD, Franco Muggia, MD
- 128. Targeted Therapy in Gynecologic Oncology
  Maurie Markman, MD
- 129. Cytoreductive Surgery and Perioperative Hyperthermic Chemotherapy for Peritoneal Carcinomatosis
  Paul H. Sugarbaker, MD, FACS, FRCS
- 130. Technique of Intraperitoneal Chemotherapy: Normothermic and Hyperther
  C. William Helm, MB.BChir, FRCS, FACOG
- 131. Cytotoxic Trials by the Gynecologic Oncology Group
  Siriwan Tangjitgamol, MD, John Kavanagh, MD
- 132. Novel Biologic and Cytotoxic Chemotherapies in Epithelial Ovarian
  John W. Moroney, MD, Robert L. Coleman, MD
- 133. Maintenance and Consolidation Therapy in Epithelial Ovarian Cancer
  Robert F. Ozols, MD, PhD
- 134. Choosing Treatments for Recurrent Ovarian Cancer: The Platinum-Free Interval
  Ashley Stuckey, MD, Don S. Dizon, MD, FACP
- 135. Chemotherapy in Cervical Cancer
  Margaret Liotta, DO, Peter G. Rose, MD
- 136. Chemotherapy in Endometrial Cancer
  Ozden Altundag, MD, Esra Kuscu, MD
- 137. Immunotherapy in Uterine Cancers
  An Coosemans, MD, PhD, Sandra Tuyaerts, PhD Anke Vanderstraeten, MD, Frederic Amant, MD, PhD
- 138. Neoadjuvant Chemotherapy in Cervical Cancer
  Juan E. Sardi, MD, PhD
- 139 Management of Chemotherapy Induced Adverse Effects
  Nicanor I. Barrena Medel, MD, Thomas J. Herzog, MD
SECTION VIII: RADIATION ONCOLOGY
- 140. Principles of Radiation Therapy in Gynecologic Oncology
  Banu Atalar, MD, Enis Ozyar, MD
- 141. Current Radiotherapy Protocols in Gynecologic Oncology
  William Small, Jr., MD, FACRO, FACR Jonathan B. Strauss, MD
- 142. Stereotactic Body Radiosurgery in Gynecologic Carcinomas
  Charles A. Kunos, MD, PhD, Yuxia Zhang, MS James Brindle, PhD
- 143. Image Guided vs. Conventional Radiation Therapy in Gynecologic Cancers
  Alina Sturdza, MD, FRCPC, Maximilian Schmid, MD, Richard Pötter, MD
- 144. Chemoradiotherapy for Gynaecologic Cancers
  Nermina Kantardzic, MD, PhD, Mirela Kalamujic, MD Daniela Trokic , MD
- 145. Radiotherapy for Cervical Cancer
  Taran P. Hellebust, PhD, Mansoor R. Mirza, MD
- 146. Radiotherapy in Endometrial Cancer
  Thomas Hogberg, MD
- 147. Use of Preoperative Biomarkers to Identify High Risk Endometrial Carcinoma Patients
  Helga Salvesen, MD, PhD, Ingeborg B. Engelsen, MD, PhD Jone Trovik, MD, PhD
- 148. Radiotherapy for Vulvar and Vaginal Cancers
  Amol J. Ghia, MD, David K. Gaffney, MD
- 149. Pelvic Irradiation: Acute and Late Toxicity
  Nermina Kantardzic, MD, PhD, Dzenana Begic, MD Dzenana Eminagic, MD
SECTION IX: PALLIATIVE CARE IN GYNECOLOGIC ONCOLOGY
- 150. Challenges and Opportunities in Palliative Care
  Giovanni Elia, MD, Frank D. Ferris, MD, FAAHPM, FAACE
- 151. Chemotherapy Induced Nausea and Vomiting
  Mohan K. Tummala, MD, MRCP, Diane Tatrow, NP William P. McGuire, MD
- 152. Chemotherapy Induced Diarrhea
  Diane Tatrow, NP, Mohan K Tummala, MD, MRCP William P McGuire, MD
- 153. Pain Palliation
  Natalie Moryl, MD
- 154. Nutrition in Cancer
  Paula Ravasco, RD, MD, PhD
- 155. Complementary and Alternative Medicine Use Among Patients with Gynaecological Cancers
  Kjell Bergfeldt, MD, PhD, Johanna Hök, MSc Pharm, PhD
- 156. Unusual Recurrences and Metastases in Gynecologic Cancers
  Erik S. Andersen, MD, DMSc
- 157. Principles of Psycho-Oncology
  Daniel P. Da Silva, MD, Rita Sousa, MD
- 158. Palliation of Advanced Ovarian Cancers
  Albert Tuca Rodriguez, MD
- 159. Ovarian Cancers: When Should Treatments Stop?
  Dace Rezeberga, MD, PhD, Ronalds Macuks, MD
- 160. Pleural Effusions and Refractory Ascites
  Ahmet Baris Guzel, MD, Mehmet Ali Vardar, MD, Aytekin Altintas MD
- 161. Euthanasia
  A. Peter M. Heintz, MD, PhD, Nicole B. Swarte, MD, PhD
- 162. Quality of Life (QoL) in Oncologic Patients
  Adriana Bermudez, MD, PhD
SECTION X: PROS, CONS AND DEBATES
- 163. Radiation Therapy in Early Endometrial Cancers
  Remi A. Nout, MD, Carien L. Creutzberg, MD, PhD
- 164. Radiotherapy in Early Endometrial Cancers: Con
  Jamie N. Bakkum-Gamez, MD, Stefano Uccella, MD Andrea Mariani, MD, Karl C. Podratz, MD, PhD
- 165. Debulking Surgery in Advanced Ovarian Cancer–Pro Primary Surgery
  Jacobus Pfisterer, MD, PhD, Philipp Harter, MD Jalid Sehouli, MD, PhD, Andreas du Bois, MD, PhD
- 166. Neoadjuvant Chemotherapy or Primary Debulking Surgery in Advanced Ovarian Cancer
  Ignace Vergote, MD, PhD, Leen Verleye, MD Toon Van Gorp, MD, Karin Leunen, MD Patrick Neven, MD, PhD, Frederic Amant, MD
- 167. The Role of Interval Debulking Surgery in the Management of Advanced Stage Ovarian Cancer
  Catherine Uzan, MD, PhD, Sebastien Gouy, MD Philippe Morice, MD, PhD
- 168. Systemic Chemotherapy in Ovarian Cancer
  Angiolo Gadducci, MD
- 169. Intraperitoneal Chemotherapy in Epithelial Ovarian Cancer: Pros and Cons
  Danijela Jelovac, MD, Deborah K. Armstrong, MD
- 170. Secondary Cytoreduction in the Treatment of Recurrent Ovarian Cancer
  Ram Eitan, MD, Dennis S. Chi, MD
- 171. Lymphadenectomy for Endometrial Cancer:
  Richard R. Barakat, MD, Elizabeth Jewell, MD, MHSc
- 172 Lymph Node Resection in Endometrial Cancer: Con
  Emma J. Crosbie, MRCOG, PhD Henry C. Kitchener, MD, FRCS, FRCOG
- 173 Role of Retroperitoneal Lymphatic Debulking in Gynecologic Cancers
  Cagatay Taskiran, MD, M. Anil Onan, MD, Haldun Guner, MD
SECTION XI: MULTI-CENTER TRIALS AND COOPERATIVE GROUPS
- 174. The EORTC Gynaecological Cancer Group: A Perspective on Its Role in European
  Clinical Trial Development Nicholas Reed, MD
- 175. Review of Major Gynecologic Oncology Group Trials in the Management of Gynecologic Cancer
  Matthew F. Kohler, MD, William T. Creasman, MD
- 176. The Role of the Gynecologic Cancer InterGroup (GCIG)
  Henry C. Kitchener, MD, FRCS, FRCOG Micheal Quinn, MB, ChB, MRCP, FRCOG, FRANZCOG, CGO
- 177. The European Network of Gynaecological Oncology Trial Groups (ENGOT)
  Ignace Vergote, MD, PhD
- 178. The European Network of Translational Research in Gynaecological Oncology (ENTRIGO) and Epigenetics as an Example for a Bench to Bedside Approach in Women’s Cancer
  Martin Widschwendter, MD, MRCOG, Allison Jones, BSc Helga Salvesen, MD, PhD, Frederic Amant, MD, PhD René Verheijen, MD, PhD, Ate G.J. van der Zee, MD
- 179. Current Status in Gynaecologic Oncology Researches in the World
  Polat Dursun, MD, Murat Gultekin, MD, Ali Ayhan, MD
SECTION XII: HISTORY OF GYNECOLOGIC ONCOLOGY
- 180. A Brief History of Gynecologic Oncology in the United States
  Krishnansu S. Tewari, MD, FACOG, FACS
- 181. A Brief History of Gynaecological Oncology in Europe
  Antonio Onnis, MD, Maria Marchetti, MD, Peter Bösze, MD
- 182. History of Radical Hysterectomy
  Polat Dursun, MD, Murat Gultekin, MD, Ali Ayhan, MD Serdar Serin, MD
- 183. History of the FIGO Staging System and Current Update
  Sergio Pecorelli, MD, PhD, FACS, Franco Odicino, MD, PhD
- 184. Palliative Medicine in Oncology: Models of Organization
  Xavier Gómez-Batiste, MD, PhD, Josep Porta-Sales, MD, PhD Jose Espinosa Rojas, MD
SECTION XIII: BREAST CANCER
- 185. How Effective are Breast Cancer Screening Programmes Doris Schopper, MD, PhD, Chris de Wolf, MD?
- 186. Investigation of Suspected Breast Cancer
  Penelope Moyle, MD, MBChB, FRCR
- 187. Surgical Treatment of Breast Cancer
  Gianluca Franceschini, MD, Daniela Terribile, MD Alba Di Leone, MD, Riccardo Masetti, PhD
- 188. Medical Treatments in Breast Cancer
  José R. Rossari, MD, MSc, Evandro de Azambuja, MD, PhD Martine Piccart-Gebhart, MD, PhD
- 189. A Review of New Therapeutic Modalities in Breast Cancer
  Paul A. Foster, MD, PhD
SECTION XIV: TRAINING IN GYNAECOLOGIC ONCOLOGY
- 190. Training in Gynaecologic Oncology Across Europe
  Ranjit Manchanda, MRCOG, Murat Gultekin, MD
- 191 Gynecologic Oncology Fellowship Training in the USA
  Oliver Zivanovic, MD, Michaela Bossart, MD
- 192. Gynaecologic Oncology Training in Australia
  Boris Vranes, MD
- 193. ESGO Training Opportunities
  Jacek P. Grabowski, MD, PhD, Ignacio Zapardiel, MD, PhD
- 194. Teaching and Learning Skills in the 21st Century: From Authority Based to Evidence Based Learning and Teaching Techniques
  Katinka Prince, MD, Cor de Kroon, MD, Pim Teunissen, MD, Jurgen M.J. Piek, MD

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ESGO is extremely proud to be associated with this unique publication and acknowledges the support and effort of all those who have been involved in the production of this book. We are extremely grateful to all contributing authors for their contributions and to editors for their tireless effort and enthusiasm in putting the textbook together.